Aplasia de medula: diagnóstico, classificação e tratamento

Abstract

Bone marrow aplasia or bone aplastic anemia is a rare disease characterized by moderate to severe pancytopenia in the peripheral blood and striking hypocellularity in the bone marrow is the most common spinal cord syndrome. MA is not easy to diagnose because several other causes of pancytopenia may offer a clinical picture similar to that of aplasia. The disease is triggered through acquired or congenital causes. Every 1,000,000 people 2 to 4 are affected by acquired AM. It has a higher incidence in individuals between 10 and 25 years of age and in those over 60 years of age, and there are no differences between the sexes. The types of existing treatments for AM correspond to the supportive treatment; Transplantation of hematopoietic stem cells (HSCT) and immunosuppressive treatment. Thus, the general objective of this study is to discuss bone marrow aplasia as well as its incidence, diagnosis and treatment modalities. The methodology used to carry out this study was through bibliographical research,