Marcadores bioquímicos do infarto do miocárdio

Abstract

Myocardial Infarction (MI), commonly known as heart attack or stroke, is caused by the death of the heart muscle due to the obstruction of blood flow from the coronary arteries to the heart. Ischemic heart disease is the major cause of death in men and women over the age of thirty and its diagnosis is made based on clinical symptoms, electrocardiograms and changes in biochemical markers of myocardial necrosis. This article reviews the biochemical markers that assist in the diagnosis of myocardial infarction: CK-T (Creatine Kinase), CK-MB (MB isoenzyme of Creatine Kinase), myoglobin, AST (Aspartate Aminotransferase), DHL (Lactate Dehydrogenase) and troponins (cTnI and cTnT), since these markers appear as safe and effective method of laboratory identification of MI. References studied are consistent in saying that myoglobin, CK-MB and troponins are more specific in the diagnosis of MI.