Fatores genéticos e doenças associadas à doença celíaca: uma revisão bibliografica

Abstract

Celiac disease is an intolerance to gluten ingestion in individuals with genetic or immunologic predisposition and is associated with various pathologies such as infertility, DMI and SD. It is characterized by inflammation of the intestinal villi may involve other organs such as liver and nervous system. The DC has a complex diagnosis, and the intestinal biopsy is the gold standard for the discovery of the disease. Thus, the objective of this study is to review literature evaluating the genetic factors and the main diseases associated with celiac disease. For this articles, magazines, editorials and guidelines for national and foreign language were used. Thus, there was that the ideas of the corresponding authors of the surveyed analyzed were consensual. Concluded that celiac disease pathogenesis is still a little known and who have untreated high mortality.