Digoxina: mecanismo de ação, tratamento, efeitos adversos e a importância na qualidade de sua manipulação

Abstract

Heart failure (HF) is a severe and chronic pathology that presented change in the function of pumping blood from the heart. There are several causes for the appearance of the disease, such as atherosclerosis, hypertension, lung disease, hypothyroidism and the elderly are individuals with presentation of various diseases, becomes a risk group for the development of HF. One of the drugs widely used for the HF is digoxin, originated from the foxglove plant. This drug plays important effects on the heart, but has a narrow therapeutic window which may induce toxicity, requiring care in the use of these drugs. The objective of this stud was to conduct a literature related to the drug digoxin. The following parameters were used for research: digitalis, masterful quality control, heart disease, digoxin, side effects of drugs with narrow therapeutic window. It was observed that despite the narrow therapeutic window, digoxin can be handled safely. In this context, the pharmacist plays an important role in guiding the manner of use of these drugs and in the process of quality control in the handling of these drugs.