Avaliação de potenciais interações medicamentosas em pacientes psiquiátricos

Abstract

Drug interaction (DI) can be set to any change in the pharmacological effect of a drug intervention because of another drug, food, drink or some chemical or environmental agent. Even though most interactions reflect negatively on the clinical condition of the patient, it is important to remember that some may be

beneficial. The main causes of DI, the most common are the practice of self- medication and polypharmacy, the latter is quite common in the field of

psychiatry. The aim of this study was to identify and evaluate potential drug interactions in hospitalized patients of male and female units of psychiatry philanthropic Vila São José Bento Cottolengo, in the county of Trindade-Go , by analyzing their respective prescriptions . The DI were classified according to the database of the website Drugs.com, being classified as "major", "moderate" and "minor." The sample included 55 prescriptions, 22 male and 33 female, with ages ranging between 18 and 75 years. A total of 570 potential DI were observed, with 9.5% classified as higher, 85.2 % as moderate and 5.3 % as lower, revealing worrying. The actual clinical significance of interactions was found not reviewed, however, the findings of this study serve to alert health professionals about the potential risk to which patients are subjected, serving as a basis for further investigation and decision making as the best way to apply pharmacologic therapy.