Uso de Vincristina em cão com Tumor Venéreo Transmissível (TVT) Relato de caso

Abstract

Transmissible Venereal Tumor (TVT) is a contagious neoplasia that affects dogs, primarily transmitted through sexual contact or social behaviors such as licking and sniffing. Diagnosis is based on clinical findings and cytology, with chemotherapy using vincristine sulfate being the treatment of choice, known for its high efficacy and low recurrence rates. This study reports the case of a mixed-breed dog with genital TVT, highlighting the therapeutic approach employed. Methodology: The patient, a 4-year-old mixed-breed dog, was rescued with penile lesions and myiasis. After unsuccessful home treatment involving cleaning and suturing, the dog was referred for veterinary care. TVT was diagnosed through cytology, and treatment with vincristine sulfate was initiated, administered intravenously over six weekly sessions. Following the completion of chemotherapy, orchiectomy was performed to prevent future diseases. The anesthetic protocol included acepromazine, dexmedetomidine, propofol, and isoflurane. Discussion: As described in the literature, TVT has a high prevalence in stray dogs, particularly in intact males. Cytology proved effective for diagnosis, confirming typical cellular characteristics of the tumor. The chemotherapy protocol followed established scientific guidelines, showing positive results with complete tumor regression. Orchiectomy was recommended as a prophylactic measure and was performed using an anesthetic protocol that ensured the animal’s safety and well-being. Conclusion: This case report confirms the efficacy of vincristine sulfate in treating TVT, combined with appropriate anesthetic and surgical protocols. Efficient clinical management not only ensured tumor remission but also contributed to preventing future complications, emphasizing the importance of early diagnosis and integrated treatment.