O uso de probióticos no tratamento da esteatose hepática

Abstract

Objective: This review article aimed to evaluate the use of probiotics in the treatment of hepatic steatosis, looking for the effect of probiotics on markers and the development of hepatic steatosis. Methodology: The PRISMA - adapted method was used, data collection was performed between April 08 and 22, 2019 on a digital platform, PUBMED (National Library of Medicine of the United States) and LILACS (Latin American and Caribbean Center of health information), where articles published between the years of 2013 to 2019 were included in this study, using the eligibility criteria, 15 studies were included on non-alcoholic hepatic steatosis, its treatment with probiotics and the effects on markers specific to the NAFLD. Results: A study carried out with mice by Ritze et al. (2014) that specific probiotic strains such as the Lactobacillus rhamnosus GG strain promoted the protection and reduction of fat in the liver and the specific markers for NAFLD regardless of the type of animal's diet. And in humans, we can highlight the study by Nabavi et al. (2014), where they used a probiotic yogurt, in which the participants presented the reduction of biochemical markers for NAFLD, as in TGP, AST, in LDL, and in total cholesterol. Conclusion: The Studies have shown significant reduction in intrahepatic lipid and markers for NAFLD. Regardless of the strains used, the results were satisfactory, demonstrating that probiotics can be used as an aid in the treatment of hepatic steatosis and control of intestinal dysbiosis.