Injúria renal aguda secúndaria a infecção uterina relato de caso

Abstract

Case report of a 12-year-old intact female Labrador Retriever diagnosed with closed pyometra and secondary acute kidney injury (AKI) due to endotoxemia. Clinical signs included lethargy, hyporexia, vomiting, locomotor difficulty, hyperthermia, and abdominal pain. Lab work showed microcytic hypochromic anemia, mild neutrophilic leukocytosis, and serum creatinine of 3.76 mg/dL. Abdominal ultrasound revealed a distended uterus with anechoic content. Therapeutic ovariohysterectomy was performed as emergency surgery. Postoperatively, the patient developed transient anuria, reversed with intensive fluid therapy, and creatinine peaked at 6.11 mg/dL. Treatment protocol included ceftriaxone, multimodal analgesia, NSAID discontinuation, maropitant as needed, and antioxidant renal support with Gerioox®. Creatinine progressively decreased to 1.81 mg/dL, with restored diuresis, appetite, and mobility. Early diagnosis, immediate surgery, appropriate fluid therapy, and intensive support were critical for AKI reversibility and safe discharge.