Uso do l-prf e i-prf pós-extração dentária em pacientes em uso de bisfosfonatos: relato de caso

Abstract

INTRODUCTION: Dentistry is full of challenging situations that require dental surgeons to have the technical and scientific knowledge to deal with them. It is of fundamental importance to know the patient as a whole in order to provide them with the best alternative to a complex case. Therefore, some patients are more at risk than others. One example is patients taking bisphosphonates who undergo more invasive treatments, especially if they have been administered for a longer period of time. Bisphosphonates are drugs used in patients suffering from bone diseases such as osteoporosis, malignant neoplasms with bone metastasis, malignant hypercalcemia and multiple myeloma. These drugs work by inhibiting osteoclastic activity and stimulating osteoblastic activity, thus reducing bone resorption; however, prolonged use of these drugs can have the side effect of osteonecrosis of the jaws (ONM). OBJECTIVES: To present a clinical case of a 74 years old female patient who had used an injectable bisphosphonate and was going to have her left lateral incisor and canine (teeth 22 and 23) extracted; bone graft, L-PRF and I-PRF grafting will be carried out, as well as discussing the biological importance of using l-PRF in this case. METHODOLOGY: The work will be carried out by means of a case report, case planning, study of complementary dental and medical examinations. EXPECTED RESULTS: It is hoped that there will be an understanding of the drug mentioned, the side effects, the importance of using reported material in this case and the pharmacodynamics of bisphosphonates. CONCLUSION: This is a case in which the interrelationship between the use of bisphosphonates and the treatment with bone graft, L-PRF and I-PRF will be presented, as the use of protective and preventive means is extremely important in a case like this.