https://dspace.unigoyazes.edu.br/handle/123456789/28 Tue, 13 Oct 2026 02:40:46 GMT 2026-10-13T02:40:46Z https://dspace.unigoyazes.edu.br/handle/123456789/2161 Título: Perfil epidemiológico da sífilis congênita e gestacional na região centro-oeste do brasil (2019-2024) Abstract: OBJECTIVE: To analyze the epidemiological profile of congenital and gestational syphilis in the Central-West region of Brazil from 2019 to 2024. METHODOLOGY: This is a descriptive and retrospective epidemiological study, conducted using secondary data obtained from the Notifiable Diseases Information System (SINAN) and the Ministry of Health. RESULTS: From 2019 to 2024, the Central-West Region registered a sustained increase in syphilis notifications. Notably, the 30-39 age group was the most affected in gestational syphilis, representing 22,770 cases, while in congenital syphilis the predominant age group among mothers was 20-29 years, with 5,280 notifications; both age groups comprise young women in their reproductive years. Regarding the sociodemographic profile, 24,858 women self-identified as mixed- race/brown, and 5,904 had low levels of education (incomplete primary education). Latent syphilis was the predominant clinical form (42%). Regarding healthcare, it was identified that in 59.00% of cases of congenital syphilis, mothers received prenatal care. CONCLUSION: The results indicate the need to strengthen public health in the areas surrounding capital cities and metropolitan regions, areas with the highest notification rates in the Central-West region. The persistence of vertical transmission is associated with the spread of the disease to the interior of the country, social vulnerability, and late diagnosis. The inclusion of clinical pharmacy is strategic to improve prenatal care, ensure adherence to Benzathine Penicillin G, and promote multidisciplinary integration, aiming to mitigate the adverse outcomes of syphilis in the region. Tipo: Trabalho de Conclusão de Curso Wed, 01 Jul 2026 00:00:00 GMT https://dspace.unigoyazes.edu.br/handle/123456789/2161 2026-07-01T00:00:00Z https://dspace.unigoyazes.edu.br/handle/123456789/2160 Título: O impacto do tratamento farmacológico na qualidade de vida de pacientes com transtorno bipolar Abstract: Objectives: To analyze the impact of pharmacological treatment on the quality of life of patients with Bipolar Disorder.Methodology: This is a qualitative literature review, conducted through the analysis of scientific articles, books, and clinical guidelines related to Bipolar Disorder and the pharmacological treatments used in the management of the disease. Results: It was observed that mood stabilizers, antipsychotics, and antidepressants play a fundamental role in controlling mood swings and reducing relapses, contributing to the improvement of the social, emotional, and cognitive functioning of patients.Conclusion or Final considerations: Pharmacological treatment is essential for the control of Bipolar Disorder, but it must be accompanied by continuous monitoring and an individualized approach, aiming for greater therapeutic adherence and better quality of life for patients. Tipo: Trabalho de Conclusão de Curso Mon, 01 Jun 2026 00:00:00 GMT https://dspace.unigoyazes.edu.br/handle/123456789/2160 2026-06-01T00:00:00Z https://dspace.unigoyazes.edu.br/handle/123456789/2159 Título: Desenvolvimento e avaliação de creme hidratante para mãos com ativos naturais: investigação de características organolépticas na adição de substâncias naturais no desenvolvimento de novas formulações Abstract: OBJECTIVES: To analyze the influence of the oil phase concentration on the development and physicochemical and sensory properties of moisturizing hand creams formulated with natural ingredients. MATERIALS AND METHODS: Experimental laboratory study with a qualitative and exploratory approach. Three formulations were developed using virgin coconut oil and sweet almond oil at different concentrations incorporated into a non-ionic cream base. The formulations were evaluated through organoleptic analysis, pH determination, and preliminary stability tests under different storage conditions. RESULTS: The oil phase concentration directly influenced viscosity, spreadability, skin absorption, and residual sensation. The 10% formulation showed higher occlusivity, while the 5% formulation presented lighter texture and faster absorption. The 7% formulation exhibited balanced sensory and functional properties. All formulations maintained satisfactory preliminary physical stability. CONCLUSION: The modulation of the oil phase proved to be essential for tailoring formulation characteristics, highlighting the potential of natural ingredients in the development of effective cosmetic products suitable for different skin types. Tipo: Trabalho de Conclusão de Curso Wed, 01 Jul 2026 00:00:00 GMT https://dspace.unigoyazes.edu.br/handle/123456789/2159 2026-07-01T00:00:00Z https://dspace.unigoyazes.edu.br/handle/123456789/2158 Título: Impacto do cuidado farmacêutico no controle glicêmico do diabetes mellitus tipo 2 em idosos: revisão integrativa Abstract: Objectives:To analyze, through an integrative literature review, the impact of pharmaceutical care on glycemic control in elderly patients with type 2 Diabetes Mellitus Methodology: This is an integrative review conducted in PubMed, SciELO, and LILACS databases, including studies published between 2015 and 2026. Original and secondary studies in Portuguese and English were included, addressing pharmaceutical interventions and glycemic outcomes. The selection followed PRISMA flowchart stages, and methodological quality was assessed using the CASP instrument.Results: A total of 17 studies were included, demonstrating that pharmaceutical care contributes to the reduction of glycated hemoglobin (HbA1c) levels, improved medication adherence, and greater disease understanding among elderly patients. Final considerations: Pharmaceutical care positively impacts glycemic control and highlights the importance of the pharmacist’s clinical role. Tipo: Trabalho de Conclusão de Curso Wed, 01 Jul 2026 00:00:00 GMT https://dspace.unigoyazes.edu.br/handle/123456789/2158 2026-07-01T00:00:00Z